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  Featured Genital Acne Article

The Power of Accutane: The Benefits and Risks of a Breakthrough Acne Drug

Acne plagued Julie Harper throughout high school and college. She depended on makeup and wore her hair down over the side of her face. She gave up chocolate and french fries, only to find that neither made a difference. And she went through medicine after medicine, from over-the-counter creams to oral antibiotics. These were not occasional pimples that vanish after a couple of days. This acne covered her face and left scars on her neck. "I had tried everything and felt frustrated all the time," says Harper, now a physician and assistant professor of dermatology at the University of Alabama-Birmingham--a career she chose due in large part to her struggle with acne.

Harper finally found a successful treatment nine years ago at the age of 22. She took a drug called isotretinoin (trade name Accutane) and watched her skin improve in just a couple of months. By the third month, her acne had disappeared. She says with clearer skin came more self-confidence and higher self-esteem. Considered the biggest breakthrough in acne drug treatment over the last 20 years, Accutane is the only drug that has the potential to clear severe acne permanently after one course of treatment. One course, which is typically five months, results in prolonged remission of acne in up to 85 percent of patients. A member of a class of drugs known as retinoids, Accutane is highly effective. But it doesn't work for everyone, and some patients need more than one course of treatment. Dr. Harper took a second course of Accutane one year after the first and has been free of severe acne ever since, now only occasionally using a topical medication.

No other acne medicine works as well for severe acne. Patients generally have to keep using other medications because they only suppress acne temporarily. But as powerful as Accutane can be in improving patients' lives, its adverse effects can be just as powerful. The drug is known to cause miscarriage and severe birth defects. Patients taking Accutane may develop potentially serious problems affecting a number of organs, including the liver, intestines, eyes, ears, and skeletal system. And some patients taking Accutane have developed serious psychiatric problems, including depression. More rarely, patients have developed suicidal behavior and killed themselves. Because it is a high-risk drug, Accutane should be reserved for cases of "severe recalcitrant nodular acne," according to the product's labeling. This type of acne is resistant to standard acne treatment, including oral antibiotics, and is characterized by many nodules or cysts--inflammatory lesions filled with pus and lodged deep within the skin. These lesions can cause pain, permanent scarring, and negative psychological effects.

 
   Additional Genital Acne Resources

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   Genital Acne News

Foamix collaborates with Warner Chilcott on acne treatment (Globes Online)
Foamix will receive an initial payment of several hundred thousand dollars, and subsequent payments based on milestones, and royalties.

Teenage Acne Treatment; No Change After 7 Months (WOAI)
Q. My 15-year-old son has been on oral and topical acne treatment (doctor prescribed) for about seven months, and his condition is worse - not better. We have done the three-month follow up and now he wants to seek another opinion. Should we? Or continue to give it a chance?

Warner Chilcott Collaborates With Foamix (AP via Yahoo! Finance)
Specialty pharmaceutical company Warner Chilcott Company Inc. said late Wednesday it will develop and market an antibiotic foam acne treatment with Foamix Ltd.

Investing in Small Cap Pharmaceuticals: Noven, Barrier, Penwest and Endo (SeekingAlpha via Yahoo! Finance)
On January 8, The Wall Street Transcript interviewed FTN Midwest Securities Corp. analyst Timothy Chiang on small cap specialty pharmaceuticals. Key excerpts follow: TWST: Why the smaller names?

Clal Biotechnology is strategic investor in Thrombotech (Globes Online)
CBI will invest $50,000 in Thrombotech's blood clot treatment.

 

 
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